2,4-Dihydroxy-6-methylbenzoic acid

Base Information

Chemical Name:2,4-Dihydroxy-6-methylbenzoic acid
CAS No.:480-64-8
Molecular Formula:C8H8O4
Molecular Weight:168.149
Hs Code.:2918290000
European Community (EC) Number:610-404-4
UNII:11XLA0494B
DSSTox Substance ID:DTXSID20197385
Nikkaji Number:J6.167K
Wikipedia:Orsellinic_acid
Wikidata:Q414421
Metabolomics Workbench ID:27911
ChEMBL ID:CHEMBL457583
Mol file:480-64-8.mol

Synonyms:orsellinic acid

Suppliers and Price of 2,4-Dihydroxy-6-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Orsellinic Acid
1mg
$ 403.00

TRC
OrsellinicAcid
10mg
$ 55.00

Labseeker
2,4-DIHYDROXY-6-METHYLBENZOICACID 95
20g
$ 1833.00

Crysdot
OrsellinicAcid 97%
100mg
$ 200.00

Crysdot
OrsellinicAcid 97%
250mg
$ 320.00

Crysdot
OrsellinicAcid 97%
1g
$ 810.00

ChemScene
Orsellinicacid
1g
$ 809.00

Chemenu
2,4-Dihydroxy-6-methylbenzoicacid 95+%
1g
$ 421.00

Cayman Chemical
Orsellinic Acid ≥98%
250mg
$ 495.00

Cayman Chemical
Orsellinic Acid ≥98%
100mg
$ 264.00

Total 35 raw suppliers

Chemical Property of 2,4-Dihydroxy-6-methylbenzoic acid

Chemical Property:

Vapor Pressure:7.89E-07mmHg at 25°C
Melting Point:173-174°C
Refractive Index:1.645
Boiling Point:391.4 °C at 760 mmHg
PKA:pK (25°) 3.90
Flash Point:204.7 °C
PSA：77.76000
Density:1.46 g/cm³
LogP:1.10440
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Ethyl Acetate (Slightly), Methanol (Slightly)
Water Solubility.:Soluble in water, dimethyl sulfoxide or 100% ethanol.
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:168.04225873
Heavy Atom Count:12
Complexity:180

Purity/Quality:

97% ^*data from raw suppliers

Orsellinic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=C1C(=O)O)O)O
Description Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.
Uses Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.

Technology Process of 2,4-Dihydroxy-6-methylbenzoic acid

There total 48 articles about 2,4-Dihydroxy-6-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 487-69-4
2,4-dihydroxy-6-methylbenzaldehyde

: 480-64-8
orsellinic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; In water; dimethyl sulfoxide;
DOI:10.1021/ol030109m

Reference yield: 95.0%

: 504-15-4
orcinol

: 124-38-9,18923-20-1
carbon dioxide

: 480-64-8
orsellinic acid

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 40 ℃; for 24h; under 15001.5 Torr; Autoclave;
DOI:10.1039/c9cc04550c