M37E3NE7QB

Base Information

Chemical Name:M37E3NE7QB
CAS No.:530084-87-8
Molecular Formula:C₃₂H₃₁N₃O₄
Molecular Weight:521.616
Hs Code.:
UNII:M37E3NE7QB
DSSTox Substance ID:DTXSID30432118
Wikidata:Q82246182
Pharos Ligand ID:1S1GFSPBL3M1
ChEMBL ID:CHEMBL3290999

Synonyms:M37E3NE7QB;530084-87-8;CHEMBL3290999;TD5471;TD-5471;2(1H)-Quinolinone, 8-hydroxy-5-((1R)-1-hydroxy-2-((2-(4-((6-methoxy(1,1'-biphenyl)-3-yl)amino)phenyl)ethyl)amino)ethyl)-;8-Hydroxy-5-((1R)-1-hydroxy-2-((2-(4-((6-methoxy(1,1'-biphenyl)-3-yl)amino)phenyl)ethyl)amino)ethyl)-2(1H)-quinolinone;N-(2-(4-((3-Phenyl-4-methoxyphenyl)amino)phenyl)ethyl)-(R)-2-hydroxy-2-(8-hydroxy-1,2-dihydro-2-oxoquinolin-5-yl)ethylamine;UNII-M37E3NE7QB;SCHEMBL246986;DTXSID30432118;LGFPFBZHAODPHC-LJAQVGFWSA-N;BDBM50018589;8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-(4-methoxy-3-phenylanilino)phenyl]ethylamino]ethyl]-1H-quinolin-2-one;N-{2-[4-(3-phenyl-4-methoxyphenyl)aminophenyl]ethyl}-(R)-2-hydroxy-2-(8-hydroxy-2(1H)-quinolinon-5-yl)ethylamine

Suppliers and Price of M37E3NE7QB

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of M37E3NE7QB

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:521.23145648
Heavy Atom Count:39
Complexity:794

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)NC2=CC=C(C=C2)CCNCC(C3=C4C=CC(=O)NC4=C(C=C3)O)O)C5=CC=CC=C5
Isomeric SMILES:COC1=C(C=C(C=C1)NC2=CC=C(C=C2)CCNC[C@@H](C3=C4C=CC(=O)NC4=C(C=C3)O)O)C5=CC=CC=C5

Technology Process of M37E3NE7QB

There total 9 articles about M37E3NE7QB which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1055276-52-2
C₄₆H₄₃N₃O₄

: 530084-87-8
TD-5471

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In acetic acid; for 17h; under 2068.65 Torr;

Reference yield:

: 530084-78-7
N-[2-[4-[(3-phenyl-4-methoxyphenyl)amino]phenyl]ethyl]-(R)-2-hydroxy-2-(8-benzyloxy-1,2-dihydro-2-oxoquinolin-5-yl)ethylamine

: 530084-87-8
TD-5471

Guidance literature:: With hydrogen; palladium on carbon; In methanol; dichloromethane; for 18h; under 760.051 Torr;

Reference yield:

: 73918-56-6
4-Bromophenethylamine

: 530084-87-8
TD-5471

Guidance literature:: Multi-step reaction with 7 steps

1: toluene

2: sodium tetrahydroborate / tetrahydrofuran; methanol

3: triethylamine / methanol

4: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate / toluene / 6 h / 95 °C

5: trifluoroacetic acid / dichloromethane

6: isopropyl alcohol / 16 h / 78 °C

7: palladium 10% on activated carbon; hydrogen / acetic acid / 2068.65 Torr

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triethylamine; trifluoroacetic acid; sodium t-butanolate; In tetrahydrofuran; methanol; dichloromethane; acetic acid; isopropyl alcohol; toluene;
DOI:10.1016/j.bmcl.2014.04.069