N-Allyl-3,4-dimethoxybenzamide

Base Information

• Chemical Name: N-Allyl-3,4-dimethoxybenzamide
• CAS No.: 73664-69-4
• Molecular Formula: C12H15NO3
• Molecular Weight: 221.256
• Hs Code.: 2924299090
• Mol file: 73664-69-4.mol

Synonyms:N-Allyl-3,4-dimethoxy-benzoesaeureamid;N-Allyl-3,4-dimethoxybenzamide;BENZAMIDE,N-ALLYL-3,4-DIMETHOXY;3,4-dimethoxy-N-(prop-2-en-1-yl)benzamide;

Chemical Property of N-Allyl-3,4-dimethoxybenzamide

Chemical Property:

• Vapor Pressure: 0.00011mmHg at 25°C
• Boiling Point: 336.8°C at 760 mmHg
• Flash Point: 157.5°C
• PSA: 51.05000
• Density: 1.074g/cm³
• LogP: 2.19440

Purity/Quality:

N-ALLYL-3,4-DIMETHOXYBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Allyl-3,4-dimethoxybenzamide

There total 2 articles about N-Allyl-3,4-dimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Veratric acid (93-07-2) + 1-amino-2-propene (107-11-9,30551-89-4) → N-allyl-3,4-dimethoxybenzamide (73664-69-4)

Guidance literature:

Veratric acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

1-amino-2-propene; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/adsc.201901262

Reference yield:

→ N-allyl-3,4-dimethoxybenzamide (73664-69-4)

Guidance literature:

3,4-Dimethoxy-benzoesaeurechlorid, Allylamin, Ae., Bzl., 2 h;

DOI:10.1021/jm00333a015

Reference yield: 82.0%

Togni's reagent II (887144-94-7) + N-allyl-3,4-dimethoxybenzamide (73664-69-4) → 2-(3,4-dimethoxyphenyl)-5-(2,2,2-trifluoroethyl)oxazoline

Guidance literature:

With potassium iodide; In 1,4-dioxane; at 80 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.jfluchem.2017.07.012

upstream raw materials:

Veratric acid

1-amino-2-propene

Downstream raw materials:

2-(3,4-dimethoxyphenyl)-5-((phenylselanyl)methyl)-4,5-dihydrooxazole

allyl 3,4-dimethoxybenzoate