Chemical Property of (7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Property:
- PKA:2.78±0.50(Predicted)
- PSA：214.20000
- Density:1.859g/cm3
- LogP:0.70170
- XLogP3:-0.9
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:11
- Rotatable Bond Count:6
- Exact Mass:453.07767569
- Heavy Atom Count:30
- Complexity:821
- Purity/Quality:
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97% *data from raw suppliers
CEFOVECIN 95.00% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C4CCCO4)C(=O)O
- Isomeric SMILES:CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2C3N(C2=O)C(=C(CS3)[C@@H]4CCCO4)C(=O)O
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Description
Cefovecin (brand name: Convenia?) is a cephalosporin antibiotic used most commonly for skin infections, periodontal disease, and urinary tract infections. It has also been used as a part of outpatient treatment for parvovirus and other bacterial infections. It is a long-acting injectable antibiotic and is therefore useful in cases when giving medications by mouth is difficult.https://vcahospitals.com/know-your-pet/cefovecin
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Uses
Cefovecin is a cephalosporin antibiotic used in the treatment of skin conditions in dogs and cats. Cefovecin is considered a third-generation cephalosporin but may not have the same activity as other injectable third-generation cephalosporins, such as cefotaxime.Cefovecin is a new extended-spectrum semisynthetic cephalosporin indicated for the treatment of bacterial infections in dogs and cats.
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Indications
Cefovecin is approved for use in dogs and cats. It is approved in the US for skin and soft tissue infections but also has been used to treat urinary tract infections, for which it is approved in some countries. The efficacy of cefovecin for treating infections in other sites, such as the respiratory tract, bone, and central nervous system, has not been established. Experience is limited to administration of cefovecin in dogs and Cats; the use in other species, such as horses, large animals, birds, and reptiles, is not recommended until specific dosing recommendations are published.
