Chemical Property of Diflorasone diacetate
Chemical Property:
- Appearance/Colour:crystals
- Melting Point:47-49°C(lit.)
- Refractive Index:1.546
- Boiling Point:585.1 °C at 760 mmHg
- PKA:12.63±0.70(Predicted)
- Flash Point:307.6 °C
- PSA:106.97000
- Density:1.31 g/cm3
- LogP:2.98530
- Storage Temp.:Refrigerator
- Solubility.:Chloroform (Slightly), Methanol (Slightly)
- Water Solubility.:6.5mg/L(22 oC)
- XLogP3:3
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:6
- Exact Mass:494.21160968
- Heavy Atom Count:35
- Complexity:1050
- Purity/Quality:
-
99%, *data from raw suppliers
Diflorasone diacetate
*data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
20/21/22-40
- Safety Statements:
22-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COC(=O)C)OC(=O)C)C)O)F)C)F
- Isomeric SMILES:C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)OC(=O)C)C)O)F)C)F
- Recent EU Clinical Trials:Determination of anti-inflammatory efficacy of topical formulations in a UV erythema test
- Recent NIPH Clinical Trials:Phase II study of M118103
-
Uses
Anti-inflammatory (topical)
-
Therapeutic Function
Antiinflammatory