N-((N,N-dimethylamino)ethyl)-5-(N,N-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

Base Information

• Chemical Name: N-((N,N-dimethylamino)ethyl)-5-(N,N-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide
• CAS No.: 142439-63-2
• Molecular Formula: C15H21 Cl2 N5 O5
• Molecular Weight: 422.268
• Mol file: 142439-63-2.mol

Synonyms:NSC 646394;SN 23816

Chemical Property of N-((N,N-dimethylamino)ethyl)-5-(N,N-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

Chemical Property:

• Vapor Pressure: 1.93E-12mmHg at 25°C
• Boiling Point: 557°Cat760mmHg
• Flash Point: 290.6°C
• PSA: 130.71000
• Density: 1.388g/cm³
• LogP: 3.69960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-((N,N-dimethylamino)ethyl)-5-(N,N-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide

There total 3 articles about N-((N,N-dimethylamino)ethyl)-5-(N,N-bis(2-chloroethyl)amino)-2,4-dinitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

N-<2-(N,N-dimethylamino)ethyl>-5-chloro-2,4-dinitrobenzamide (142439-70-1) + N,N-bis(chloro-2-ethyl)amine (334-22-5) → SN 23816 (142439-63-2)

Guidance literature:

at 50 ℃; for 1h;

DOI:10.1021/jm00095a018

Reference yield:

5-chloro-2,4-dinitrobenzoic acid (136833-36-8) → SN 23816 (142439-63-2)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / 1 h / Heating

2: acetone / 0.25 h / 0 °C

3: 56 percent / 1 h / 50 °C

With thionyl chloride; In acetone;

DOI:10.1021/jm00095a018

Reference yield:

5-chloro-2,4-dinitrobenzoyl chloride (50425-06-4) → SN 23816 (142439-63-2)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 0.25 h / 0 °C

2: 56 percent / 1 h / 50 °C

In acetone;

DOI:10.1021/jm00095a018

upstream raw materials:

N-<2-(N,N-dimethylamino)ethyl>-5-chloro-2,4-dinitrobenzamide

N,N-bis(chloro-2-ethyl)amine

5-chloro-2,4-dinitrobenzoic acid

5-chloro-2,4-dinitrobenzoyl chloride

Refernces