4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine

Base Information

• Chemical Name: 4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine
• CAS No.: 1361114-14-8
• Molecular Formula: C₄₈H₇₇NO₂Si
• Molecular Weight: 728.23
• Mol file: 1361114-14-8.mol

Synonyms:4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine

Chemical Property of 4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine

There total 1 articles about 4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

C43H74O2Si (1361114-29-5) + 4-bromopyridine hydrochloride (19524-06-2) → 4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine (1361114-14-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine; In N,N-dimethyl-formamide; at 60 ℃; for 20h; Inert atmosphere;

DOI:10.1021/jo300034h

Reference yield: 81.0%

4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine (1361114-14-8) → 4-((4,5-bis(dodecyloxy)-2-ethynylphenyl)ethynyl)pyridine (1361114-16-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at -89 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/jo300034h

Reference yield:

4-((4,5-bis(dodecyloxy)-2-((triisopropylsilyl)ethynyl)phenyl)-ethynyl)pyridine (1361114-14-8) → 2,5-bis((4,5-bis(dodecyloxy)-2-(pyridin-4-ylethynyl)phenyl)-ethynyl)pyrazine (1361113-94-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / -89 °C / Inert atmosphere

2: copper(l) iodide; bis(benzonitrile)palladium(II) dichloride; diisopropylamine; XPhos / N,N-dimethyl-formamide / 72 h / 70 °C / Inert atmosphere

With copper(l) iodide; bis(benzonitrile)palladium(II) dichloride; tetrabutyl ammonium fluoride; diisopropylamine; XPhos; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/jo300034h

upstream raw materials:

C₄₃H₇₄O₂Si

4-bromopyridine hydrochloride

Downstream raw materials:

4-((4,5-bis(dodecyloxy)-2-ethynylphenyl)ethynyl)pyridine

2,5-bis((4,5-bis(dodecyloxy)-2-(pyridin-4-ylethynyl)phenyl)-ethynyl)pyrazine

2,3-bis((4,5-bis(dodecyloxy)-2-(pyridin-4-ylethynyl)phenyl)-ethynyl)pyrazine