7-iodo-2-quinoxalinol

Base Information

• Chemical Name: 7-iodo-2-quinoxalinol
• CAS No.: 347162-77-0
• Molecular Formula: C₈H₅IN₂O
• Molecular Weight: 272.045
• Mol file: 347162-77-0.mol

Synonyms:7-iodo-2-quinoxalinol

Chemical Property of 7-iodo-2-quinoxalinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 7-iodo-2-quinoxalinol

There total 1 articles about 7-iodo-2-quinoxalinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-iodo-2-nitroaniline (20691-72-9) → 7-iodo-2-quinoxalinol (347162-77-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 7 percent / 1 h / 125 °C

2: Fe; aq. conc. HCl / methanol / 2 h / Heating

3: 3percent aq. H₂O₂; aq. NaOH / 1 h / Heating

With hydrogenchloride; sodium hydroxide; iron; In methanol;

DOI:10.1021/jm0005149

Reference yield: 36.0%

7-iodo-2-quinoxalinol (347162-77-0) → 2-chloro-7-iodoquinoxaline (347162-16-7)

Guidance literature:

With trichlorophosphate; for 1h; Heating;

DOI:10.1021/jm0005149

Reference yield:

7-iodo-2-quinoxalinol (347162-77-0) → 2-[4-(7-iodo-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester (347162-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 36 percent / POCl₃ / 1 h / Heating

2: 82 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With potassium carbonate; trichlorophosphate; In acetonitrile;

DOI:10.1021/jm0005149

upstream raw materials:

4-iodo-2-nitroaniline

Downstream raw materials:

2-chloro-7-iodoquinoxaline

2-[4-(7-iodo-quinoxalin-2-yloxy)-phenoxy]-propionic acid methyl ester