3,5-Diethyl-2-propylpyridine

Base Information

• Chemical Name: 3,5-Diethyl-2-propylpyridine
• CAS No.: 4808-75-7
• Molecular Formula: C12H19 N
• Molecular Weight: 177.29
• European Community (EC) Number: 225-371-8
• DSSTox Substance ID: DTXSID30197412
• Nikkaji Number: J262.468K
• Wikidata: Q83070290
• Mol file: 4808-75-7.mol

Synonyms:3,5-Diethyl-2-propylpyridine;4808-75-7;3,5-diethyl-2-n-propylpyridine;2-Propyl-3,5-diethylpyridine;EINECS 225-371-8;4-NITROCINNAMICACID;2-propyl 3,5-diethylpyridine;3,5-diethyl-2-propyl-pyridine;SCHEMBL10981034;DTXSID30197412;2-n-Propyl-3.5-diethyl pyridine;Pyridine, 3,5-diethyl-2-propyl-;AKOS006228486;FT-0614583;A827464

Chemical Property of 3,5-Diethyl-2-propylpyridine

Chemical Property:

• Vapor Pressure: 0.0345mmHg at 25°C
• Boiling Point: 250.4°Cat760mmHg
• PKA: 6.65±0.20(Predicted)
• Flash Point: 94.9°C
• PSA: 12.89000
• Density: 0.897g/cm³
• LogP: 3.15890
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 177.151749610
• Heavy Atom Count: 13
• Complexity: 133

Purity/Quality:

98%min ^*data from raw suppliers

3,5-DIETHYL-2-N-PROPYLPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/38:Irritating to eyes and skin.
• Hazard Codes: R36/38:Irritating to eyes and skin.
• Statements: R36/38:Irritating to eyes and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

Useful:

• Canonical SMILES: CCCC1=C(C=C(C=N1)CC)CC

Technology Process of 3,5-Diethyl-2-propylpyridine

There total 24 articles about 3,5-Diethyl-2-propylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.8%

→ 2-Propyl-3,5-diethyl pyridine (4808-75-7) + 1-butyl-2-propyl-3,5-diethyl-1,2-dihydropyridine (63789-05-9)

Guidance literature:

Reference yield: 82.0%

butyraldehyde (123-72-8) → 2-Propyl-3,5-diethyl pyridine (4808-75-7)

Guidance literature:

With ammonium hydroxide; PrCl₃*6H₂O; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1134/S1070428007090291

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + butan-1-ol (71-36-3) → 3,5-diethylpyridine (699-25-2) + 2-Propyl-3,5-diethyl pyridine (4808-75-7)

Guidance literature:

With ammonia; at 350 ℃; under 760.051 Torr; Temperature; Reagent/catalyst; Inert atmosphere; Flow reactor;

DOI:10.1134/S0023158419020022

upstream raw materials:

1-(-)-2-amino-1-butanol

3,5-diethyl-1-benzyl-2-propyl-1,2-dihydro-pyridine

butyraldehyde

2r,4c,6c-tripropyl-hexahydro-[1,3,5]triazine

Refernces

• 1、 Agliullin, M. R.,Bikbaeva, V. R.,Bubennov, S. V.,Filippova, N. A.,Gataulin, A. R.,Grigor’eva, N. G.,Kostyleva, S. A.,Kutepov, B. I.,Narender, Nama. "Mesoporous Aluminosilicates in the Synthesis of N-Heterocyclic Compounds". . p. 733 - 743. Retrieved 2020/02/25.
• 2、 Selimov, F. A.,Akhmetov, A. Zh.,Dzhemilev, U. M.. "SYNTHESIS OF ALYKL SUBSTITUTED PYRIDINES BY LIQUID PHASE CONDENSATION OF ALDEHYDES WITH AMINES UNDER THE ACTION OF COMPLEXED METAL CATALYSTS". . p. 1893 - 1895. Retrieved 2007/10/02.