benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Chemical Name:benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate
CAS No.:1174913-74-6
Molecular Formula:C₂₇H₂₈BrN₅O₄
Molecular Weight:566.454
Hs Code.:

Synonyms:benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Chemical Property of benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

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Technology Process of benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

There total 1 articles about benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1174913-73-5
benzyl (S)-morpholin-2-ylmethylcarbamate

: 370866-02-7
5-bromo-4-chloro-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine

: 1174913-74-6
benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

Guidance literature:: With triethylamine; In butan-1-ol; at 160 ℃; for 3.5h; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm900314j

Reference yield: 59.0%

: 1174913-74-6
benzyl (R)-(4-(5-bromo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

: 98-80-6
phenylboronic acid

: 1174913-81-5
benzyl (R)-(4-(1-(4-methoxybenzyl)-5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl)methylcarbamate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate; In water; acetonitrile; at 140 ℃; for 0.5h; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm900314j