2-chlorobenzenesulfinic acid sodium salt

Base Information

• Chemical Name: 2-chlorobenzenesulfinic acid sodium salt
• CAS No.: 15946-36-8
• Molecular Formula: C₆H₄ClO₂S*Na
• Molecular Weight: 198.605
• Mol file: 15946-36-8.mol

Synonyms:2-chlorobenzenesulfinic acid sodium salt

Chemical Property of 2-chlorobenzenesulfinic acid sodium salt

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

sodium2-chlorobenzene-1-sulfinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chlorobenzenesulfinic acid sodium salt

There total 5 articles about 2-chlorobenzenesulfinic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.8%

2-chlorobenzenesulphinic acid (45750-59-2) → 2-chlorobenzenesulfinic acid sodium salt (15946-36-8)

Guidance literature:

With sodium hydroxide; In methanol; water; at 40 ℃; for 2h;

Reference yield: 92.0%

2-chlorophenylsulfonyl chloride (2905-23-9) → 2-chlorobenzenesulfinic acid sodium salt (15946-36-8)

Guidance literature:

With sodium hydrogencarbonate; sodium sulfite; In water; at 80 ℃; for 4h;

DOI:10.1021/acs.orglett.9b01218

Reference yield: 68.0%

→ 2-chlorobenzenesulfinic acid sodium salt (15946-36-8)

Guidance literature:

With iron(III) chloride; rongalite; In N,N-dimethyl-formamide; acetonitrile; at 20 ℃; for 0.333333h;

upstream raw materials:

2-chlorophenylsulfonyl chloride

2-Chlorobenzeneboronic acid

2-chlorobenzenesulphinic acid

Downstream raw materials:

o-Chlor-phenylsulfonylacetamid

2-(2-chlorobenzenesulfonyl)pyridine-3-carbaldehyde

2-((2-chlorophenyl)thio)tetrahydrofuran

2-((2-chlorophenyl)sulfonyl)-1-phenylethan-1-one

Refernces

• 1、 -. "Styrene sulfone NLRP3 inflammasome inhibitor, preparation method and application thereof". . . Retrieved 2020/10/30.
• 2、 Bogonda, Ganganna,Patil, DIlip V.,Kim, Hun Young,Oh, Kyungsoo. "Visible-Light-Promoted Thiyl Radical Generation from Sodium Sulfinates: A Radical-Radical Coupling to Thioesters". supporting information. p. 3774 - 3779. Retrieved 2019/05/24.