1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride

Base Information

Chemical Name:1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride
CAS No.:327973-79-5
Molecular Formula:C₁₈H₂₈N₄O₄*ClH
Molecular Weight:400.906
Hs Code.:

Synonyms:1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride

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Chemical Property of 1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride

Chemical Property:

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Technology Process of 1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride

There total 1 articles about 1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 327973-78-4
1-[4-(N-Z-aminomethyl)-phenyl]-2,3-di-Boc-guanidine

: 327973-79-5
1-(4-aminomethyl)-phenyl-2,3-di-Boc-guanidine hydrochloride

Guidance literature:: 1-[4-(N-Z-aminomethyl)-phenyl]-2,3-di-Boc-guanidine; With hydrogen; palladium 10% on activated carbon; In ethanol; for 1h;

With hydrogenchloride; In 1,4-dioxane; di-isopropyl ether; water; isopropyl alcohol;

Reference yield: 60.0%

: 327973-79-5
1-(4-aminomethyl)-phenyl-2,3-di-Boc-guanidine hydrochloride

: 4457-32-3
4-nitrobenzyl chloroformate

: 4-[N-(4-nitrobenzyloxycarbonyt)-aminomethyl]-phenylguanidine hydrochloride

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 327973-79-5
1-[4-(aminomethyl)phenyl]-2,3-di-tert-butyloxycarbonyl-guanidine hydrochloride

: 25774-02-1
monobenzyl phenylmalonate

: 362467-57-0
N-[4-(2,3-bis-Bocguanidino)benzyl] 2-(benzyl-oxycarbonyl)-2-phenylacetamide

Guidance literature:: With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In ethyl acetate; N,N-dimethyl-formamide;