(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

Base Information

Chemical Name:(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate
CAS No.:1268870-82-1
Molecular Formula:C₁₉H₃₀N₂O₅
Molecular Weight:366.458
Hs Code.:

Synonyms:(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

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Chemical Property of (2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

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Technology Process of (2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

There total 1 articles about (2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: (2S)-methyl 6-(benzylamino)-2-[bis(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

: 1268870-82-1
(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.25h;
DOI:10.1055/s-0030-1258275

Reference yield: 92.0%

: 1268870-82-1
(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

: (2S)-2-[(tert-butoxycarbonyl)amino]-5-hydroxy-N-benzylcaprolactam

Guidance literature:: In ethanol; for 48h; Reflux;
DOI:10.1055/s-0030-1258275

Reference yield: 18.0%

: 1268870-82-1
(2S)-methyl 6-(benzylamino)-2-[(tert-butoxycarbonyl)amino]-5-hydroxyhexanoate

: 1268870-84-3
(2S,5R)-2-[(tert-butoxycarbonyl)amino]-5-hydroxy-N-benzylcaprolactam

: 144090-66-4
(2S,5S)-2-[(tert-butoxycarbonyl)amino]-5-hydroxycaprolactam

: 270902-68-6
(3S, 6R)-3-(tert-butoxycarbonyl)aminohexahydro-6-hydroxy-2H-azepin-2-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; optical yield given as %de; Reflux;
DOI:10.1055/s-0030-1258275