C₆₆H₁₀₁NO₁₂Si₂

Base Information

• Chemical Name: C₆₆H₁₀₁NO₁₂Si₂
• CAS No.: 197250-11-6
• Molecular Formula: C₆₆H₁₀₁NO₁₂Si₂
• Molecular Weight: 1156.7
• Mol file: 197250-11-6.mol

Synonyms:C₆₆H₁₀₁NO₁₂Si₂

Chemical Property of C₆₆H₁₀₁NO₁₂Si₂

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₁₀₁NO₁₂Si₂

There total 5 articles about C₆₆H₁₀₁NO₁₂Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C69H107NO12Si2 (197250-10-5) → C66H101NO12Si2 (197250-11-6)

Guidance literature:

With 3,3-dimethyldioxirane; In acetone; at -50 - -26 ℃; for 2.16667h;

DOI:10.1016/S0040-4020(97)00866-1

Reference yield:

C72H112INO13Si2 → C66H101NO12Si2 (197250-11-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 110 percent / C₈K-ZnCl₂-AgOAc / tetrahydrofuran / 1 h / 0 °C

2: 100 percent / dimethyl dioxirane / acetone / 2.17 h / -50 - -26 °C

With C₈K-ZnCl₂-AgOAc; 3,3-dimethyldioxirane; In tetrahydrofuran; acetone; 1: Reduction / 2: Oxidation;

DOI:10.1016/S0040-4020(97)00866-1

Reference yield:

C80H121NO15Si2 → C66H101NO12Si2 (197250-11-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / DDQ / CH₂Cl₂; H₂O / 0.83 h / 20 °C

2: 88 percent / triphenylphosphine; imidazole; iodine / toluene / 0.5 h / 70 °C

3: 110 percent / C₈K-ZnCl₂-AgOAc / tetrahydrofuran / 1 h / 0 °C

4: 100 percent / dimethyl dioxirane / acetone / 2.17 h / -50 - -26 °C

With 1H-imidazole; C₈K-ZnCl₂-AgOAc; iodine; 3,3-dimethyldioxirane; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane; water; acetone; toluene; 1: Oxidation / 2: Substitution / 3: Reduction / 4: Oxidation;

DOI:10.1016/S0040-4020(97)00866-1

upstream raw materials:

C₆₉H₁₀₇NO₁₂Si₂

Downstream raw materials:

Tacrolimus

Refernces