N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Base Information

Chemical Name:N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester
CAS No.:110337-90-1
Molecular Formula:C₆₂H₈₀N₄O₂₃
Molecular Weight:1249.33
Hs Code.:

N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Synonyms:N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Suppliers and Price of N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

There total 6 articles about N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 13139-16-7
N-(tert-butyloxycarbonyl)-L-isoleucine

: 110337-89-8
O-<(2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

: 110337-90-1
N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Guidance literature:: With N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; In dichloromethane; 1.) 1 h, - 20 deg C 2.) 18 h, room temperature;
DOI:10.1016/S0008-6215(00)90004-1

Reference yield:

: 87376-57-6
2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide

: 110337-90-1
N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Guidance literature:: Multi-step reaction with 6 steps

1: 71 percent / AgClO₄, 4A molecular sieves / CH₂Cl₂; toluene / 23 h / -30 °C

2: 1.) H₂S 2.) pyridin / 1.) water, 0 deg C for 5 h then room temperature for 18 h 2.) 3 h, room temperature

3: 97 percent / 85percent formic acid / Pd-Mohr / methanol / 0.25 h

4: 95 percent / 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / CH₂Cl₂ / 1.) 1 h, -25 deg C 2.) 18 h, room temperature

5: 86 percent / morpholine / 0.45 h / Ambient temperature

6: 97 percent / 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / CH₂Cl₂ / 1.) 1 h, - 20 deg C 2.) 18 h, room temperature

With morpholine; pyridine; formic acid; 4 A molecular sieve; hydrogen sulfide; silver perchlorate; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; Pd-Mohr; In methanol; dichloromethane; toluene;
DOI:10.1016/S0008-6215(00)90004-1

Reference yield:

: N-(9-Fluorenylmethoxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-azido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin-benzylester

: 110337-90-1
N-(tert-Butyloxycarbonyl)-L-isoleucyl-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-seryl-L-valin-benzylester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) H₂S 2.) pyridin / 1.) water, 0 deg C for 5 h then room temperature for 18 h 2.) 3 h, room temperature

2: 97 percent / 85percent formic acid / Pd-Mohr / methanol / 0.25 h

3: 95 percent / 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / CH₂Cl₂ / 1.) 1 h, -25 deg C 2.) 18 h, room temperature

4: 86 percent / morpholine / 0.45 h / Ambient temperature

5: 97 percent / 2-ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline / CH₂Cl₂ / 1.) 1 h, - 20 deg C 2.) 18 h, room temperature

With morpholine; pyridine; formic acid; hydrogen sulfide; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; Pd-Mohr; In methanol; dichloromethane;
DOI:10.1016/S0008-6215(00)90004-1