Laurixamine

Base Information

• Chemical Name: Laurixamine
• CAS No.: 7617-74-5
• Molecular Formula: C15H33 N O
• Molecular Weight: 243.433
• Hs Code.: 2922199090
• European Community (EC) Number: 231-528-1
• NSC Number: 166448
• UNII: WY0R7196HP
• DSSTox Substance ID: DTXSID3046241
• Nikkaji Number: J32.522H
• Wikidata: Q27293024
• NCI Thesaurus Code: C80856
• ChEMBL ID: CHEMBL1887483
• Mol file: 7617-74-5.mol

Synonyms:lauryloxypropylamine

Chemical Property of Laurixamine

Chemical Property:

• Appearance/Colour: clear colorless to light yellow liquid
• Vapor Pressure: 0.000114mmHg at 25°C
• Melting Point: 13 ºC
• Refractive Index: 1.4455-1.4485
• Boiling Point: 315 ºC
• Flash Point: 165 ºC
• PSA: 35.25000
• Density: 0.845
• LogP: 4.97300
• Storage Temp.: 2-8°C
• Water Solubility.: <0.1 g/L (20℃)
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 14
• Exact Mass: 243.256214676
• Heavy Atom Count: 17
• Complexity: 128

Purity/Quality:

99% ^*data from raw suppliers

[3-(Dodecyloxy)propyl]amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xi
• Statements: 34-22-36/37/38
• Safety Statements: 45-37/39-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCOCCCN

Technology Process of Laurixamine

There total 6 articles about Laurixamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1-(3-azidopropoxy)dodecane (1380680-79-4) → 3-(dodecyloxy)-1-propylamine (7617-74-5)

Guidance literature:

1-(3-azidopropoxy)dodecane; With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 0.166667h;

With water; In tetrahydrofuran; at 20 ℃; for 28h;

DOI:10.1016/j.bmc.2012.03.065

Reference yield:

3-dodecyloxy-propionitrile (56637-94-6) → 3-(dodecyloxy)-1-propylamine (7617-74-5)

Guidance literature:

With hydrogen; Ni(Raney);

DOI:10.1016/0008-6215(91)80165-J

Reference yield:

1-dodecyl alcohol (112-53-8) → 3-(dodecyloxy)-1-propylamine (7617-74-5)

Guidance literature:

Multi-step reaction with 2 steps

2: hydrogen / Ni(Raney)

With hydrogen; Ni(Raney);

DOI:10.1016/0008-6215(91)80165-J

upstream raw materials:

3-dodecyloxy-propionitrile

1-dodecyl alcohol

1-(3-azidopropoxy)dodecane

1-dodecylbromide

Downstream raw materials:

4-(3-lauryloxy)propyl-1,2,4-triazol

4-chloromethyl-5-methyl-2-{4-(3-dodecyloxypropyl)carbamoyl-2-nitrophenyl}-4-isoxazolin-3-one

5-t-butyl-4-chloromethyl-2-{4-(3-dodecyloxypropyl)carbamoyl-2-nitrophenyl}-4-isoxazolin-3-one

1-(3-dodecyloxy-propyl)-4-(2-methoxy-phenyl)-piperazine

Refernces

• 1、 -. "Process for production of ether amine". Example 2; comparative 2. . Retrieved 2008/06/13.