(S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester

Base Information

• Chemical Name: (S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester
• CAS No.: 69977-78-2
• Molecular Formula: C₂₆H₂₀N₂O₆
• Molecular Weight: 456.455

Synonyms:(S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester

Chemical Property of (S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester

Chemical Property:

Purity/Quality:

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Technology Process of (S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester

There total 5 articles about (S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

→ (3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester (69977-78-2,70005-63-9,73573-54-3)

Guidance literature:

Reference yield:

(S)-5-((S)-carboxy-phthalimido-methyl)-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester (69977-74-8) → (S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester (69977-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd

With hydrogen; palladium;

DOI:10.1021/ja00498a056

Reference yield:

(RS)-5-((RS)-carboxy-phthalimido-methyl)-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester (69977-74-8,70005-59-3,73573-52-1) → (RS)-((RS)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid benzhydryl ester (69977-78-2,70005-63-9,73573-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd

With hydrogen; palladium;

DOI:10.1021/ja00498a056

upstream raw materials:

(S)-((S)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid

diazodiphenylmethane

(S)-5-((S)-carboxy-phthalimido-methyl)-3-oxo-isoxazolidine-2-carboxylic acid benzyl ester

(RS)-((RS)-3-oxo-isoxazolidin-5-yl)-phthalimido-acetic acid

Downstream raw materials:

(αS,5S)-3-methoxy-4,5-dihydro-α-phthalimido-5-isoxazole acetic acid, benzhydryl ester

(S)-((S)-3-chloro-4,5-dihydro-isoxazol-5-yl)-phthalimido-acetic acid benzhydryl ester

(RS)-((RS)-3-chloro-4,5-dihydro-isoxazol-5-yl)-phthalimido-acetic acid

(RS)-((RS)-3-chloro-4,5-dihydro-isoxazol-5-yl)-phthalimido-acetic acid benzhydryl ester

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