((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione
CAS No.:99603-79-9
Molecular Formula:C₁₀H₁₄N₂O₅
Molecular Weight:242.232
Hs Code.:

Synonyms:((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Suppliers and Price of ((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of ((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

There total 3 articles about ((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59967-83-8,99603-79-9,149560-38-3
1-(2,3-dihydroxy-4-hydroxymethyl-cyclopentyl)-1H-pyrimidine-2,4-dione

Guidance literature:: XIII, 2 N oder 0.5 N H2SO4 oder 15 N NH3;

Reference yield:

: 79200-57-0
(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxylmethyl)-1-aminocyclopentan hydrochloride

: 99603-79-9
((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine; 1H-imidazole / 96 h / 20 - 50 °C

2.1: dichloromethane; toluene / 18.16 h / -78 - 20 °C

2.2: 3 h / 90 °C

With pyridine; 1H-imidazole; In dichloromethane; toluene;
DOI:10.1021/acs.orglett.1c03936

Reference yield:

: C₂₄H₅₅NO₃Si₃

: 174230-82-1
β-methoxyacryloyl isocyanate

: 99603-79-9
((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:: C₂₄H₅₅NO₃Si₃; β-methoxyacryloyl isocyanate; In dichloromethane; toluene; at -78 - 20 ℃; for 18.16h;

With hydrogenchloride; water; In ethanol; at 90 ℃; for 3h;
DOI:10.1021/acs.orglett.1c03936