ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Base Information

Chemical Name:ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate
CAS No.:1352342-92-7
Molecular Formula:C₂₃H₂₅NO₄
Molecular Weight:379.456
Hs Code.:
Mol file:1352342-92-7.mol

Synonyms:ethyl 6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Suppliers and Price of ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl6-(benzyloxy)-8-(tert-butyl)-4-hydroxyquinoline-2-carboxylate 97%
1g
$ 1062.00

Chemenu
Ethyl6-(benzyloxy)-8-(tert-butyl)-4-hydroxyquinoline-2-carboxylate 97%
1g
$ 1000.00

Alichem
Ethyl6-(benzyloxy)-8-(tert-butyl)-4-hydroxyquinoline-2-carboxylate
1g
$ 1171.04

Total 0 raw suppliers

Chemical Property of ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Chemical Property:

Purity/Quality:: Ethyl6-(benzyloxy)-8-(tert-butyl)-4-hydroxyquinoline-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

There total 5 articles about ethyl-6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1352342-91-6
4-(benzyloxy)-2-(tert-butyl)aniline

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 1352342-92-7
ethyl 6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Guidance literature:: In diethyl ether; at 60 - 200 ℃; for 1.25h; Inert atmosphere;

Reference yield:

: 6310-21-0
2-(1,1-dimethylethyl)-benzenamine

: 1352342-92-7
ethyl 6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate; iodine / dichloromethane; water / 1.5 h / 0 °C

2: copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; caesium carbonate / toluene / 23 h / 80 - 110 °C / Inert atmosphere

3: diethyl ether / 1.25 h / 60 - 200 °C / Inert atmosphere

With copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; iodine; sodium hydrogencarbonate; caesium carbonate; In diethyl ether; dichloromethane; water; toluene;

Reference yield:

: 2-(tert-butyl)-4-iodoaniline

: 1352342-92-7
ethyl 6-(benzyloxy)-8-tert-butyl-4-hydroxyquinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; caesium carbonate / toluene / 23 h / 80 - 110 °C / Inert atmosphere

2: diethyl ether / 1.25 h / 60 - 200 °C / Inert atmosphere

With copper(l) iodide; 3,4,7,8-Tetramethyl-o-phenanthrolin; caesium carbonate; In diethyl ether; toluene;