N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide

Base Information

Chemical Name:N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide
CAS No.:518050-99-2
Molecular Formula:C₁₇H₂₀ClN₃O₃
Molecular Weight:349.817
Hs Code.:

Synonyms:N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide

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Chemical Property of N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide

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Technology Process of N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide

There total 1 articles about N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 6972-27-6
1,3-Dimethyl-6-chlorouracil

: 185950-64-5
5-chloro-2-(pivaloylamino)benzeneboronic acid

: 518050-99-2
N-[4-chloro-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)phenyl]pivalamide

Guidance literature:: 1,3-Dimethyl-6-chlorouracil; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 20 ℃; for 0.333333h;

5-chloro-2-(pivaloylamino)benzeneboronic acid; With sodium carbonate; In 1,2-dimethoxyethane; for 8h; Heating;
DOI:10.1016/S0040-4020(02)01400-X