N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

Base Information

Chemical Name:N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran
CAS No.:99385-59-8
Molecular Formula:C₁₆H₁₅F₂NO₂
Molecular Weight:291.297
Hs Code.:

Synonyms:N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

Chemical Property:

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Technology Process of N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

There total 5 articles about N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 99385-77-0
6-hydroxy-1,2,3,4-tetrahydrobenzopyran-7-carboxaldehyde

: 99385-59-8
N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

Guidance literature:: With sodium borohydrid; In methanol;

Reference yield:

: 99385-82-7
7-{[(E)-2,4-Difluoro-phenylimino]-methyl}-chroman-6-ol

: 99385-59-8
N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

Guidance literature:: With sodium tetrahydroborate; In methanol; Yield given;

Reference yield:

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 99385-59-8
N-(2,4-difluorophenyl)-7-(aminomethyl)-6-hydroxy-1,2,3,4-tetrahydrobenzopyran

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / Heating

2: NaBH₄ / methanol

With sodium tetrahydroborate; In methanol;