1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea

Base Information

• Chemical Name: 1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea
• CAS No.: 93849-28-6
• Molecular Formula: C₂₅H₃₂ClN₃O₈
• Molecular Weight: 537.997

Synonyms:1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea

Chemical Property of 1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea

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Technology Process of 1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea

There total 1 articles about 1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-2-<<2-amino>ethoxy>methyl>-6-methyl-1,4-dihydropyridine (88150-58-7) + methyl isocyanate (624-83-9) → 1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea (93849-28-6)

Guidance literature:

In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jm00168a041

Reference yield: 84.0%

1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-1-<(methoxycarbonyl)methyl>-3-methylurea (93849-28-6) → 4-(2-Chloro-phenyl)-2-methyl-6-[2-(3-methyl-2,4-dioxo-imidazolidin-1-yl)-ethoxymethyl]-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester (97290-28-3)

Guidance literature:

With sodium hydride; In methanol; for 1h; Ambient temperature;

DOI:10.1021/jm00168a041

upstream raw materials:

4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-2-<<2-amino>ethoxy>methyl>-6-methyl-1,4-dihydropyridine

methyl isocyanate

Downstream raw materials:

4-(2-Chloro-phenyl)-2-methyl-6-[2-(3-methyl-2,4-dioxo-imidazolidin-1-yl)-ethoxymethyl]-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester

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