N-isopropyl 4-amino-benzoamidine hydrochloride

Base Information

• Chemical Name: N-isopropyl 4-amino-benzoamidine hydrochloride
• CAS No.: 1312776-33-2
• Molecular Formula: C₁₀H₁₅N₃*ClH
• Molecular Weight: 213.71
• Mol file: 1312776-33-2.mol

Synonyms:N-isopropyl 4-amino-benzoamidine hydrochloride

Chemical Property of N-isopropyl 4-amino-benzoamidine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-isopropyl 4-amino-benzoamidine hydrochloride

There total 2 articles about N-isopropyl 4-amino-benzoamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-benzimidic acid ethyl ester; hydrochloride + isopropylamine (75-31-0) → N-isopropyl 4-amino-benzoamidine hydrochloride (1312776-33-2)

Guidance literature:

In ethanol; at 20 ℃; for 24h;

DOI:10.1016/j.ejmech.2014.09.079

Reference yield:

4-Aminobenzonitrile (873-74-5) → N-isopropyl 4-amino-benzoamidine hydrochloride (1312776-33-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / 0 - 20 °C

2: ethanol / 24 h / 20 °C

With hydrogenchloride; In ethanol;

DOI:10.1016/j.ejmech.2014.09.079

Reference yield: 53.0%

2,6-Pyridinedicarbonyl dichloride (3739-94-4) + N-isopropyl 4-amino-benzoamidine hydrochloride (1312776-33-2) → C27H31N7O2*2ClH

Guidance literature:

2,6-Pyridinedicarbonyl dichloride; N-isopropyl 4-amino-benzoamidine hydrochloride; With triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; for 48h; Reflux;

With hydrogenchloride; In ethanol;

DOI:10.1016/j.ejmech.2011.04.001

upstream raw materials:

4-Aminobenzonitrile

isopropylamine