Chemical Property of Nogalamycine
Chemical Property:
- Vapor Pressure:7.49E-35mmHg at 25°C
- Melting Point:195-196° (dec)
- Refractive Index:1.7650 (estimate)
- Boiling Point:899.9°Cat760mmHg
- PKA:7.45 (60% ethanol)
- Flash Point:498.1°C
- PSA：229.44000
- Density:1.49g/cm3
- LogP:1.13800
- Storage Temp.:2-8°C
- XLogP3:1.1
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:17
- Rotatable Bond Count:8
- Exact Mass:787.30513448
- Heavy Atom Count:56
- Complexity:1530
- Purity/Quality:
-
99%, *data from raw suppliers
Nogalamycin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:T
- Statements:
45-46-61-20/21/22
- Safety Statements:
53-22-36/37/39-45
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1C(C(C(C(O1)OC2CC(C(C3=CC4=C(C(=C23)O)C(=O)C5=C(C=C6C(=C5C4=O)OC7C(C(C(C6(O7)C)O)N(C)C)O)O)C(=O)OC)(C)O)OC)(C)OC)OC
- Isomeric SMILES:C[C@H]1[C@@H]([C@@]([C@H]([C@@H](O1)OC2CC(C(C3=CC4=C(C(=C23)O)C(=O)C5=C(C=C6C(=C5C4=O)OC7C(C(C(C6(O7)C)O)N(C)C)O)O)C(=O)OC)(C)O)OC)(C)OC)OC
-
Uses
Nogalamycin is an unusual anthracycline produced by Streptomyces nogalater var. nogalater, reported by researchers at Upjohn in 1965. Nogalamycin contains two saccharides. The neutral monosaccharide attaches to the D ring, similar to the aminoglycoside moieties of the doxorubicin class, while the second, basic saccharide attaches to the phenolic group on the A ring in the ortho position to form a unique family of hexacyclic anthracyclines. Nogalamycin is potent antibacterial and antitumor agent that interacts with DNA by intercalation. Nogalamycin (cas# 1404-15-5) is a compound useful in organic synthesis.
