2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

Base Information

• Chemical Name: 2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide
• CAS No.: 1361953-19-6
• Molecular Formula: C₄₃H₅₄N₄O₄
• Molecular Weight: 690.926

Synonyms:2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

Chemical Property of 2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

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Technology Process of 2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

There total 1 articles about 2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-(tert-butyldimethylsilanyloxy)ethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide (1361953-18-5) → 2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide (1361953-19-6)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 20 ℃; for 24h;

Reference yield:

2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide (1361953-19-6) → 2-((S)-1-{9-[(R)-2-(3-formylamino-4-hydroxyphenyl)-2-hydroxyethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

Guidance literature:

With hydrogen; palladium on activated carbon; In ethanol; for 12h;

upstream raw materials:

2-((S)-1-{9-[(R)-2-(4-benzyloxy-3-formylaminophenyl)-2-(tert-butyldimethylsilanyloxy)ethylamino]nonyl}pyrrolidin-3-yl)-2,2-diphenylacetamide

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