(S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

Base Information

Chemical Name:(S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride
CAS No.:702689-73-4
Molecular Formula:C₃₃H₃₈F₃N₃O₃*ClH
Molecular Weight:618.139
Hs Code.:

Synonyms:(S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

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Chemical Property of (S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

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Technology Process of (S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

There total 2 articles about (S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 702692-51-1
C₄₄H₅₈F₃N₃O₈

: 702689-73-4
(S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

Guidance literature:: C₄₄H₅₈F₃N₃O₈; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 6h;

With N-ethyl-N,N-diisopropylamine; In dichloromethane;

With hydrogenchloride; In methanol;

Reference yield:

: 702692-77-1
C₂₆H₂₉N₃O₃

: 454-63-7
3-(trifluoromethyl)cyclohexan-1-ol

: 702689-73-4
(S,S)-6-(4-amino-butyl)-3-naphthalen-2-ylmethyl-1-[4-(3-trifluoromethyl-cyclohexyloxy)-benzyl]-piperazine-2,5-dione hydrochloride

Guidance literature:: C₂₆H₂₉N₃O₃; 3-(trifluoromethyl)cyclohexan-1-ol; With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at -30 - 20 ℃; for 48h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 6h;

With N-ethyl-N,N-diisopropylamine; In dichloromethane;