methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Base Information

Chemical Name:methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside
CAS No.:1332832-49-1
Molecular Formula:C₁₉H₂₆F₂O₅
Molecular Weight:372.409
Hs Code.:

Synonyms:methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Suppliers and Price of methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

There total 7 articles about methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1332832-48-0
methyl 3-O-benzyl-2-deoxy-2-fluoro-6-O-pivaloyl-4-O-trifluoromethanesulfonyl-α-D-mannopyranoside

: 1332832-49-1
methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

: 1332832-46-8
methyl 3-O-benzyl-2-deoxy-2-fluoro-6-O-pivaloyl-α-D-mannopyranoside

Guidance literature:: With tetrabutyl ammonium fluoride; tert-butyl alcohol; In tetrahydrofuran; at 23 - 60 ℃; for 4h;
DOI:10.1016/j.jfluchem.2011.05.017

Reference yield:

: 94160-77-7
methyl 2-O-trifluoromethanesulfonyl-3-O-benzyl-(R)-4,6-O-benzylidene-α-D-glucopyranoside

: 1332832-49-1
methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: tetrabutyl ammonium fluoride; water / acetonitrile / 2.5 h / 90 °C

2: hydrogenchloride; water / methanol; dichloromethane / 16 h / 23 °C

3: dmap; triethylamine / dichloromethane / 6.25 h / 0 - 23 °C

4: pyridine / dichloromethane / 1.25 h / -15 - 23 °C

5: tetrabutyl ammonium fluoride; tert-butyl alcohol / tetrahydrofuran / 4 h / 23 - 60 °C

With pyridine; hydrogenchloride; dmap; tetrabutyl ammonium fluoride; water; triethylamine; tert-butyl alcohol; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1016/j.jfluchem.2011.05.017

Reference yield:

: 76419-48-2
methyl 4,6-O-benzylidene-3-O-benzyl-α-D-glucopyranoside

: 1332832-49-1
methyl 3-O-benzyl-2,4-dideoxy-2,4-difluoro-6-O-pivaloyl-α-D-talopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine / dichloromethane / 1.25 h / -15 - 23 °C

2: tetrabutyl ammonium fluoride; water / acetonitrile / 2.5 h / 90 °C

3: hydrogenchloride; water / methanol; dichloromethane / 16 h / 23 °C

4: dmap; triethylamine / dichloromethane / 6.25 h / 0 - 23 °C

5: pyridine / dichloromethane / 1.25 h / -15 - 23 °C

6: tetrabutyl ammonium fluoride; tert-butyl alcohol / tetrahydrofuran / 4 h / 23 - 60 °C

With pyridine; hydrogenchloride; dmap; tetrabutyl ammonium fluoride; water; triethylamine; tert-butyl alcohol; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1016/j.jfluchem.2011.05.017