Technology Process of 7-{(1R,2R)-2-[3-(4-Amino-3-iodo-phenyl)-propylamino]-cyclopentyl}-heptanoic acid
There total 5 articles about 7-{(1R,2R)-2-[3-(4-Amino-3-iodo-phenyl)-propylamino]-cyclopentyl}-heptanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium acetate buffer; chloroamine-T; sodium iodide;
In
methanol;
for 0.166667h;
DOI:10.1021/jm00388a029
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 4A molecular sieves, 2.) NaBH4 / 1.) methanol, 24 h, 2.) methanol, 30 min
2: 96 percent / H2 / 10percent Pd/C / ethanol / 1810.02 Torr / Ambient temperature
3: 80 percent / 2.5percent aq. NaOH / 4 h / Heating
4: 50 percent / sodium acetate buffer, sodium iodide, chloramine-T / methanol / 0.17 h
With
sodium hydroxide; sodium tetrahydroborate; sodium acetate buffer; 4 A molecular sieve; hydrogen; chloroamine-T; sodium iodide;
palladium on activated charcoal;
In
methanol; ethanol;
DOI:10.1021/jm00388a029
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) 4A molecular sieves, 2.) NaBH4 / 1.) methanol, 24 h, 2.) methanol, 30 min
2: 96 percent / H2 / 10percent Pd/C / ethanol / 1810.02 Torr / Ambient temperature
3: 80 percent / 2.5percent aq. NaOH / 4 h / Heating
4: 50 percent / sodium acetate buffer, sodium iodide, chloramine-T / methanol / 0.17 h
With
sodium hydroxide; sodium tetrahydroborate; sodium acetate buffer; 4 A molecular sieve; hydrogen; chloroamine-T; sodium iodide;
palladium on activated charcoal;
In
methanol; ethanol;
DOI:10.1021/jm00388a029
