6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Base Information

Chemical Name:6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide
CAS No.:87203-97-2
Molecular Formula:BrH*C₁₇H₁₉NO₂
Molecular Weight:350.255
Hs Code.:
DSSTox Substance ID:DTXSID101007418

Synonyms:6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide;1,2,3,4-Tetrahydro-1-methyl-3-(4-methylphenyl)-6,7-isoquinolinediol hydrobromide;6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-methyl-3-(4-methylphenyl)-, hydrobromide;87203-97-2;DTXSID101007418;LS-85631;1-Methyl-3-(4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol--hydrogen bromide (1/1)

Suppliers and Price of 6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Chemical Property:

Vapor Pressure:8.8E-09mmHg at 25°C
Boiling Point:451.8°C at 760 mmHg
Flash Point:154.4°C
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:349.06774
Heavy Atom Count:21
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2=CC(=C(C=C2CC(N1)C3=CC=C(C=C3)C)O)O.Br

Technology Process of 6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

There total 4 articles about 6,7-Dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87203-88-1
N-<2-(3,4-dimethoxyphenyl)-1-(4-tolyl)ethyl>acetamide

: 87203-97-2
6,7-dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

2: 1.) 20 percent NH₄OH, 2.) BBr₃ / 2.) chloroform, 0 deg C, 1 h; R_.T_. 6 h; ethanol, 30 min.

With ammonium hydroxide; boron tribromide;
DOI:10.1135/cccc19831447

Reference yield:

: 87203-61-0
2-(3,4-dimethoxyphenyl)-1-(4-tolyl)ethylamine hydrochloride

: 87203-97-2
6,7-dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / pyridine / 1.) R_.T_. 3 h, 2.) overnight

3: 1.) 20 percent NH₄OH, 2.) BBr₃ / 2.) chloroform, 0 deg C, 1 h; R_.T_. 6 h; ethanol, 30 min.

With ammonium hydroxide; boron tribromide; In pyridine;
DOI:10.1135/cccc19831447

Reference yield:

: 87203-94-9
6,7-dimethoxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride

: 87203-97-2
6,7-dihydroxy-1-methyl-3-(4-tolyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide

Guidance literature:: With ammonium hydroxide; boron tribromide; Yield given. Multistep reaction; 2.) chloroform, 0 deg C, 1 h; R_.T_. 6 h; ethanol, 30 min.;
DOI:10.1135/cccc19831447