N,N'-diphenyl-N''-benzoylguanidine

Base Information

• Chemical Name: N,N'-diphenyl-N''-benzoylguanidine
• CAS No.: 5067-80-1
• Molecular Formula: C₂₀H₁₇N₃O
• Molecular Weight: 315.374
• Mol file: 5067-80-1.mol

Synonyms:N,N'-diphenyl-N''-benzoylguanidine

Chemical Property of N,N'-diphenyl-N''-benzoylguanidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-diphenyl-N''-benzoylguanidine

There total 8 articles about N,N'-diphenyl-N''-benzoylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1-benzoyl-3-phenylthiourea (4921-82-8) + aniline (62-53-3) → N,N'-diphenyl-N''-benzoylguanidine (5067-80-1)

Guidance literature:

With triethylamine; mercury dichloride; In N,N-dimethyl-formamide; at 5 ℃;

DOI:10.1016/j.ejmech.2011.11.029

Reference yield: 25.0%

dimethyl N-benzoyldithiocarbonimidate (24786-18-3) + aniline (62-53-3) → N,N'-diphenyl-N''-benzoylguanidine (5067-80-1)

Guidance literature:

In ethanol; for 4h; Heating;

Reference yield:

Benzoyl isothiocyanate (532-55-8) → N-benzoyl-N',N''-diphenyl-guanidine (5067-80-1)

Guidance literature:

Multi-step reaction with 2 steps

1: carbon tetrachloride / durch Chlorieren

2: benzene

With tetrachloromethane; benzene;

DOI:10.1021/ja02203a007

upstream raw materials:

dimethyl N-benzoyldithiocarbonimidate

aniline

N-Benzoylamino-dithiokohlensaeuremethylester

1-benzoyl-3-phenylthiourea

Downstream raw materials:

diphenylguanidine

diphenylguanidine

Refernces

• 1、 Murtaza, Ghulam,Rauf, Muhammad Khawar,Badshah, Amin,Ebihara, Masahiro,Said, Muhammad,Gielen, Marcel,De Vos, Dick,Dilshad, Erum,Mirza, Bushra. "Synthesis, structural characterization and in vitro biological screening of some homoleptic copper(II) complexes with substituted guanidines". experimental part. p. 26 - 35. Retrieved 2012/03/26.