cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine

Base Information

• Chemical Name: cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine
• CAS No.: 1246777-46-7
• Molecular Formula: C₂₀H₂₃NO₈
• Molecular Weight: 405.405
• Mol file: 1246777-46-7.mol

Synonyms:cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine

Chemical Property of cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine

There total 1 articles about cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3,4-cis-dihydroxy-pyrrolidine-1-carboxylic acid benzyl ester (122225-42-7) + Allyl chloroformate (2937-50-0) → cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine (1246777-46-7)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2010.06.060

Reference yield:

cis-3,4-diallyloxycarbonyloxy-1-benzyloxycarbonylpyrrolidine (1246777-46-7) → (+)-cis-3-allyloxy-1-benzyloxycarbonyl-4-hydroxypyrrolidine + (-)-cis-3-allyloxycarbonyloxy-1-benzyloxycarbonyl-4-hydroxypyrrolidine + 3,4-cis-dihydroxy-pyrrolidine-1-carboxylic acid benzyl ester (122225-42-7)

Guidance literature:

With immobilized Candida antarctica lipase A; water; In 1,4-dioxane; at 30 ℃; for 192h; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.tet.2010.06.060

upstream raw materials:

3,4-cis-dihydroxy-pyrrolidine-1-carboxylic acid benzyl ester

Allyl chloroformate

Downstream raw materials:

3,4-cis-dihydroxy-pyrrolidine-1-carboxylic acid benzyl ester