(E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide

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Chemical Name:(E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide
CAS No.:1174570-72-9
Molecular Formula:C₃₁H₃₄F₃N₅O₃
Molecular Weight:581.638
Hs Code.:

Synonyms:(E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide

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Chemical Property of (E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide

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Technology Process of (E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide

There total 1 articles about (E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 1174571-62-0
(E)-[2-(3-{4-[1-(2-Morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acryloylamino)-phenyl]-carbamic acid tert-butyl ester

: 1174570-72-9
(E)-N-(2-Amino-phenyl)-3-{4-[1-(2-morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acrylamide

Guidance literature:: (E)-[2-(3-{4-[1-(2-Morpholin-4-yl-ethylamino)-1-(4-trifluoromethyl-phenylcarbamoyl)-ethyl]-phenyl}-acryloylamino)-phenyl]-carbamic acid tert-butyl ester; With hydrogenchloride; In methanol; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In methanol; pH=6 - 7;