(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Base Information

Chemical Name:(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester
CAS No.:617708-77-7
Molecular Formula:C₂₈H₃₃N₃O₄
Molecular Weight:475.588
Hs Code.:

(3,5-bis-phenethylcarbamoyl-4<i>H</i>-pyridin-1-yl)-acetic acid isopropyl ester

Synonyms:(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Suppliers and Price of (3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

There total 4 articles about (3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1-(isopropyloxycarbonylmethyl)-3,5-bis(N-β-phenethylcarbamoyl)pyridinium bromide

: 617708-77-7
(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Guidance literature:: With sodium dithionite; sodium hydrogencarbonate; In diethyl ether; water; for 3h;
DOI:10.1016/S0968-0896(03)00038-5

Reference yield:

: 499-81-0
3,5-Pyridinedicarboxylic acid

: 617708-77-7
(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethyl chloroformate; triethylamine / CH₂Cl₂ / 1 h

1.2: 80 percent / CH₂Cl₂ / 6 h

2.1: 81 percent / methanol / Heating

3.1: 66 percent / sodium bicarbonate; sodium dithionite / H₂O; diethyl ether / 3 h

With sodium dithionite; chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0968-0896(03)00038-5

Reference yield:

: 64-04-0
phenethylamine

: 617708-77-7
(3,5-bis-phenethylcarbamoyl-4H-pyridin-1-yl)-acetic acid isopropyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethyl chloroformate; triethylamine / CH₂Cl₂ / 1 h

1.2: 80 percent / CH₂Cl₂ / 6 h

2.1: 81 percent / methanol / Heating

3.1: 66 percent / sodium bicarbonate; sodium dithionite / H₂O; diethyl ether / 3 h

With sodium dithionite; chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0968-0896(03)00038-5