rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester

Base Information

• Chemical Name: rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester
• CAS No.: 85485-01-4
• Molecular Formula: C₁₉H₁₉NO₄
• Molecular Weight: 325.364
• Mol file: 85485-01-4.mol

Synonyms:rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester

Chemical Property of rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester

There total 1 articles about rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl glycidate (4538-50-5) + 5-benzyloxy-1H-indole (1215-59-4) → rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester (85485-01-4)

Guidance literature:

With tin(IV) chloride; In tetrachloromethane; at 15 ℃; for 0.833333h;

DOI:10.1002/jlac.198319830207

Reference yield: 95.0%

rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester (85485-01-4) → rac-3-(5-Benzyloxy-3-indolyl)milchsaeure (85485-02-5)

Guidance literature:

With sodium hydroxide; In methanol; water; at 55 - 60 ℃; for 0.5h;

DOI:10.1002/jlac.198319830207

Reference yield:

rac-3-(5-Benzyloxy-3-indolyl)milchsaeure-methylester (85485-01-4) → rac-4-<5-Benzyloxy-2-(formamido)phenyl>-2-hydroxy-4-oxobuttersaeure (85485-04-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / 6 N NaOH / methanol; H₂O / 0.5 h / 55 - 60 °C

2: 1) O₃, 2) H₂ / 2) 5percent Pd/C / 1) methanol

With sodium hydroxide; hydrogen; ozone; palladium on activated charcoal; In methanol; water;

DOI:10.1002/jlac.198319830207

upstream raw materials:

methyl glycidate

5-benzyloxy-1H-indole

Downstream raw materials:

rac-3-(5-Benzyloxy-3-indolyl)milchsaeure

rac-3-(5-Hydroxy-3-indolyl)milchsaeure

rac-4-<5-Benzyloxy-2-(formamido)phenyl>-2-hydroxy-4-oxobuttersaeure

Refernces