4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride

Base Information

• Chemical Name: 4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride
• CAS No.: 1111646-71-9
• Molecular Formula: C₁₉H₁₉NO₄*ClH
• Molecular Weight: 361.825
• Mol file: 1111646-71-9.mol

Synonyms:4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride

Chemical Property of 4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride

There total 1 articles about 4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

diethyl 2-[1-(diphenylmethyl)azetidin-3-yl]propane-1,3-dioate (181941-94-6) → 4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride (1111646-71-9)

Guidance literature:

diethyl 2-[1-(diphenylmethyl)azetidin-3-yl]propane-1,3-dioate; With sodium hydroxide; In ethanol; water; for 16h;

With hydrogenchloride; In water;

DOI:10.3987/COM-08-11463

Reference yield: 91.0%

4-[(diphenylmethylamino)methyl]-2-oxotetrahydrofuran-3-carboxylic acid hydrochloride (1111646-71-9) → 4-[(diphenylmethylamino)methyl]-4,5-dihydrofuran-2(3H)-one (1111646-72-0)

Guidance literature:

at 130 ℃; for 2h; under 1.50015 Torr; Heating;

DOI:10.3987/COM-08-11463

upstream raw materials:

diethyl 2-[1-(diphenylmethyl)azetidin-3-yl]propane-1,3-dioate

Downstream raw materials:

4-[(diphenylmethylamino)methyl]-4,5-dihydrofuran-2(3H)-one