1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione

Base Information

• Chemical Name: 1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione
• CAS No.: 81189-49-3
• Molecular Formula: C₂₉H₂₄NO₂P
• Molecular Weight: 449.489
• Mol file: 81189-49-3.mol

Synonyms:1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione

Chemical Property of 1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione

There total 3 articles about 1-p-tolyl-3-(triphenyl-λ⁵-phosphanylidene)-pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-p-tolylphenylmaleimide (1631-28-3,25989-85-9) + triphenylphosphine (603-35-0) → 1-p-tolyl-3-(triphenyl-λ5-phosphanylidene)-pyrrolidine-2,5-dione (81189-49-3)

Guidance literature:

In acetic acid; at 20 ℃; for 0.5h;

DOI:10.1055/s-2002-28519

Reference yield:

4-methylmaleanilic acid (24870-11-9) → 1-p-tolyl-3-(triphenyl-λ5-phosphanylidene)-pyrrolidine-2,5-dione (81189-49-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Ac₂O; NaOAc / 2 h / 70 °C

2: acetic acid / 0.5 h / 20 °C

With sodium acetate; acetic anhydride; In acetic acid;

DOI:10.1055/s-2002-28519

Reference yield:

p-toluidine (106-49-0,12221-03-3) → 1-p-tolyl-3-(triphenyl-λ5-phosphanylidene)-pyrrolidine-2,5-dione (81189-49-3)

Guidance literature:

Multi-step reaction with 3 steps

1: toluene / 1 h / 20 °C

2: acetic anhydride; sodium acetate / 1.5 h / Reflux

3: acetone / Reflux

With sodium acetate; acetic anhydride; In acetone; toluene;

DOI:10.1002/jhet.2199

upstream raw materials:

N-p-tolylphenylmaleimide

triphenylphosphine

4-methylmaleanilic acid

p-toluidine

Downstream raw materials:

(E)-3-decylidene-1-p-tolyl-pyrrolidine-2,5-dione

(E)-3-tetradecylidene-1-p-tolyl-pyrrolidine-2,5-dione

3-butylidene-1-(4-tolyl)pyrrolidine-2,5-dione

(E)-3-hexylidene-1-p-tolyl-pyrrolidine-2,5-dione