Dimethylglyoxime

Base Information

• Chemical Name: Dimethylglyoxime
• CAS No.: 95-45-4
• Molecular Formula: C4H8N2O2
• Molecular Weight: 116.12
• Hs Code.: 29280090
• Mol file: 95-45-4.mol

Synonyms:2,3-Butanedione,dioxime (8CI,9CI);2,3-Diisonitrosobutane;Biacetyl dioxime;Chugaev's reagent;2,3-Butanedione,2,3-dioxime;NSC 9;Reagents, Chugaev's;Diacetyl dioxime;

Chemical Property of Dimethylglyoxime

Chemical Property:

• Appearance/Colour: white crystalline powder
• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 240-241 °C(lit.)
• Refractive Index: 1.487
• Boiling Point: 271.529 °C at 760 mmHg
• PKA: pK1:10.60 (25°C)
• Flash Point: 158.376 °C
• PSA: 65.18000
• Density: 1.17 g/cm³
• LogP: 0.68660
• Storage Temp.: 2-8°C
• Solubility.: Soluble in alcohol, acetone, ether
• Water Solubility.: INSOLUBLE

Purity/Quality:

99% ^*data from raw suppliers

Dimethylglyoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,T,F
• Statements: 22-20/21/22-25-11
• Safety Statements: 22-24/25-36-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dimethylglyoxime is used as nickel-specific complexing reagent; determination of palladium. Detection and determination of Ni and its separation from Co and many other metals. Forms a scarlet red ppt with Ni even in dil solutions. Separation of Pd from Sn, Au, Rh, and Ir, also to detect Bi with which it forms a bright yellow color and ppt. Dimethylglyoxime is specific for nickel(II) ions in ammoniacal solution if alkali tartrate is employed as masking agent to keep in solution the possibly interfering hydrolysing salts.

Technology Process of Dimethylglyoxime

There total 59 articles about Dimethylglyoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

hydrogenchloride (7647-01-0,15364-23-5) + triphenylantimony dimethylglyoximate → triphenylantimony dichloride (594-31-0,34716-91-1,20265-29-6) + butane-2,3-dione dioxime (95-45-4)

Guidance literature:

In hydrogenchloride; react. antimony compd. with concd. HCl;

DOI:10.1023/A:1019634307064

Reference yield: 95.0%

dimethylglyoxal (431-03-8) → butane-2,3-dione dioxime (95-45-4)

Guidance literature:

With pyridine; hydroxylamine hydrochloride; In methanol; for 1h; Reflux;

DOI:10.1021/acs.orglett.8b01970

Reference yield: 35.0%

butane-2,3-dione mono-oxime (135636-66-7) → 2-(1-hydroxyiminoethyl)-2,4,5-trimethyl-2H-imidazole 1-oxide (89356-40-1) + butane-2,3-dione dioxime (95-45-4)

Guidance literature:

With ammonium carbonate; In ethanol; water; for 72h; Heating;

upstream raw materials:

2-acetylpropanoic acid ethyl ester

diacetyldioxime monomethylether

2,3-dinitro-butane

ethyl methyl ketone oxime

Downstream raw materials:

butane-2,3-dione-bis(O,O'-trimethylsilyloxime)

Diacetyldioxim-bis-(1,3,5-tri-tert-butyl-4-oxo-cyclohexa-2,5-dienyl)-ether

C₁₈H₃₈N₈S₂

C₁₈H₂₀N₂O₆S₂

Refernces

• 1、 Sconyers, David J.,Blakemore, James D.. "Distinguishing between homogeneous and heterogeneous hydrogen-evolution catalysis with molecular cobalt complexes". . p. 7286 - 7289. Retrieved 2017.
• 2、 Delgado, Kyle R.,Youmans, Dustin D.,Diver, Steven T.. "Mild Isomerization of Conjugated Dienes Using Co-Mediated Hydrogen Atom Transfer". supporting information. p. 750 - 754. Retrieved 2020/01/31.
• 3、 Biancalana, Lorenzo,Batchelor, Lucinda K.,Dyson, Paul J.,Zacchini, Stefano,Schoch, Silvia,Pampaloni, Guido,Marchetti, Fabio. "α-Diimine homologues of cisplatin: synthesis, speciation in DMSO/water and cytotoxicity". supporting information. p. 17453 - 17463. Retrieved 2018/11/02.