Chemical Property of 1,6-Anhydro-beta-D-mannopyranose
Chemical Property:
- Appearance/Colour:White crystalline solid
- Vapor Pressure:0mmHg at 25°C
- Melting Point:182-184 °C
- Refractive Index:1.62
- Boiling Point:383.754 °C at 760 mmHg
- Flash Point:185.888 °C
- PSA:79.15000
- Density:1.689 g/cm3
- LogP:-2.17580
- Storage Temp.:2-8°C
- Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
- XLogP3:-2.1
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:0
- Exact Mass:162.05282342
- Heavy Atom Count:11
- Complexity:161
- Purity/Quality:
-
99% *data from raw suppliers
1,6-Anhydro-b-D-mannopyranose *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn,
Xi
- Hazard Codes:Xi,Xn
- Statements:
20/21/22-36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1C2C(C(C(C(O1)O2)O)O)O
- Isomeric SMILES:C1[C@@H]2[C@H]([C@@H]([C@@H]([C@H](O1)O2)O)O)O
-
General Description
1,6-Anhydro-β-D-mannopyranose (AMP) is a selectively synthesized anhydrosugar derived from the microwave-assisted dehydration of methyl-α-D-mannopyranoside (MαMP) in sulfolane, yielding high selectivity (96% AMP) under optimized conditions (240 °C). It can also undergo regioselective acylation catalyzed by Pseudomonas fluorescens lipase, preferentially targeting the axial 4-OH group, enabling the synthesis of monoesters that are challenging to produce via conventional methods.