3-Hydroxy-5-cholestenoic acid

Base Information

Chemical Name:3-Hydroxy-5-cholestenoic acid
CAS No.:6561-58-6
Molecular Formula:C₂₇H₄₄O₃
Molecular Weight:416.645
Hs Code.:
DSSTox Substance ID:DTXSID70984186
Nikkaji Number:J676.103H
Wikidata:Q27154973
Mol file:6561-58-6.mol

Synonyms:3 beta-hydroxy-5-cholesten-26-oic acid;3 beta-hydroxy-5-cholestenoic acid;3-HCOA;3-hydroxy-5-cholesten-26-oic acid;3-hydroxy-5-cholestenoic acid;3-hydroxy-5-cholestenoic acid, (3beta,25R)-isomer;3-hydroxy-5-cholestenoic acid, (3beta,25S)-isomer;3-hydroxy-5-cholestenoic acid, 26-14(C)-labeled;3-hydroxycholest-5-en-26-oic acid

Suppliers and Price of 3-Hydroxy-5-cholestenoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3β-Hydroxy-5-cholestenoicAcid
1mg
$ 185.00

Cayman Chemical
3β-hydroxy-5-Cholestenoic Acid ≥95%
500μg
$ 162.00

Cayman Chemical
3β-hydroxy-5-Cholestenoic Acid ≥95%
1mg
$ 307.00

American Custom Chemicals Corporation
3-BETA-HYDROXY-5-CHOLESTENOIC ACID 95.00%
5MG
$ 499.27

Total 4 raw suppliers

Chemical Property of 3-Hydroxy-5-cholestenoic acid

Chemical Property:

Vapor Pressure:1.86E-14mmHg at 25°C
Melting Point:178-180°C
Boiling Point:551.4°C at 760 mmHg
Flash Point:301.4°C
PSA：57.53000
Density:1.08g/cm³
LogP:6.45340
Storage Temp.:Refrigerator
XLogP3:7.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:416.32904526
Heavy Atom Count:30
Complexity:684

Purity/Quality:

97% ^*data from raw suppliers

3β-Hydroxy-5-cholestenoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCCC(C)C(=O)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
Isomeric SMILES:C[C@H](CCCC(C)C(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
Uses A metabolite of Cholesterol. Elimination of Cholesterol in human endothelial cells

Technology Process of 3-Hydroxy-5-cholestenoic acid

There total 13 articles about 3-Hydroxy-5-cholestenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50681-37-3
27-hydroxycholesterol 3-acetate

: 6561-58-6
3β-hydroxy-5-cholestenoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Jones reagent / acetone / 0.25 h / Ambient temperature

2: KOH, methanol

With methanol; potassium hydroxide; jones reagent; In acetone;
DOI:10.1016/0039-128X(93)90048-R

Reference yield:

: 148988-35-6
(3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-(tert-Butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

: 6561-58-6
3β-hydroxy-5-cholestenoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / Ambient temperature

2: acetic acid, water / tetrahydrofuran / Ambient temperature

3: Jones reagent / acetone / 0.25 h / Ambient temperature

4: KOH, methanol

With pyridine; methanol; potassium hydroxide; jones reagent; water; acetic acid; In tetrahydrofuran; acetone;
DOI:10.1016/0039-128X(93)90048-R

Reference yield:

: 148988-36-7
Acetic acid (3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

: 6561-58-6
3β-hydroxy-5-cholestenoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid, water / tetrahydrofuran / Ambient temperature

2: Jones reagent / acetone / 0.25 h / Ambient temperature

3: KOH, methanol

With methanol; potassium hydroxide; jones reagent; water; acetic acid; In tetrahydrofuran; acetone;
DOI:10.1016/0039-128X(93)90048-R