(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Base Information

Chemical Name:(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid
CAS No.:131449-86-0
Molecular Formula:C₄₂H₅₁N₉O₁₁
Molecular Weight:857.921
Hs Code.:

(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Synonyms:(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Suppliers and Price of (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

There total 4 articles about (S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3392-11-8
2,5-dioxopyrrolidin-1-yl N-(tert-butoxycarbonyl)-L-tryptophanate

: 131449-86-0
(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 11.9 g / N-methylmorpholine / dimethylformamide / 18 h / 0 - 20 °C

2: 3.95 g / H₂ / 10percent Pd/C / 18 h / 760 Torr / Ambient temperature

3: N-methylmorpholine / dimethylformamide / 18 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm960509y

Reference yield:

: 131450-40-3
H-Lys(CBz)-Asp(OBn)-Phe-NH₂ hydrochloride

: 131449-86-0
(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 11.9 g / N-methylmorpholine / dimethylformamide / 18 h / 0 - 20 °C

2: 3.95 g / H₂ / 10percent Pd/C / 18 h / 760 Torr / Ambient temperature

3: N-methylmorpholine / dimethylformamide / 18 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm960509y

Reference yield:

: 131450-41-4
(S)-3-{(S)-6-Benzyloxycarbonylamino-2-[(S)-2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid benzyl ester

: 131449-86-0
(S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-[3-(2-nitro-phenyl)-ureido]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 3.95 g / H₂ / 10percent Pd/C / 18 h / 760 Torr / Ambient temperature

2: N-methylmorpholine / dimethylformamide / 18 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm960509y