2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne

Base Information

• Chemical Name: 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne
• CAS No.: 1023280-91-2
• Molecular Formula: C₂₉H₃₃NO₂
• Molecular Weight: 427.587
• Mol file: 1023280-91-2.mol

Synonyms:2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne

Chemical Property of 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne

There total 6 articles about 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-cyanobromobenzene (6952-59-6) + 1,4-diethynyl-2,5-bis-hexyloxy-benzene (128424-37-3) → 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne (1023280-91-2)

Guidance literature:

With piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 80 ℃; for 12h;

DOI:10.1039/b718348h

Reference yield:

C38H53NO2Si → 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne (1023280-91-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h;

DOI:10.1039/c1cc10577a

Reference yield:

C31H50O2Si (1312919-38-2) → 2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethyne (1023280-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1 h / 65 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h

With piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1039/c1cc10577a

upstream raw materials:

3-cyanobromobenzene

1,4-diethynyl-2,5-bis-hexyloxy-benzene

C₃₁H₅₀O₂Si

1,4-bis(hexyloxy)-2-ethynyl-5-(2-triisopropylsilylethynyl)benzene

Downstream raw materials:

2-(4-bromophenyl)-5-(4-{[4-(3-cyanophenylethynyl)-2,5-bis(hexyloxy)phenyl]ethynyl}phenyl)-1,3,4-oxadiazole

2-[4-({4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethynyl)phenyl]-5-(4-{2-[4-(2-phenylethynyl)-2,5-bis(hexyloxy)phenyl]ethynyl}phenyl)-1,3,4-oxadiazole

2,5-bis[4-(2-{4-[2-(3-cyanophenyl)ethynyl]-2,5-bis(hexyloxy)phenyl}ethynyl)phenyl]-1,3,4-oxadiazole

2-(4-bromophenyl)-5-{4-[4-(3-cyanophenylethynyl)-2,5-bis(hexyloxy)phenyl]ethynylphenyl}-1,3,4-thiadiazole