N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide

Base Information

• Chemical Name: N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide
• CAS No.: 32255-42-8
• Molecular Formula: C₁₉H₂₃NO₄
• Molecular Weight: 329.396
• Mol file: 32255-42-8.mol

Synonyms:N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide

Chemical Property of N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide

There total 2 articles about N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

isochroman-3-one (4385-35-7) + 2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide (32255-42-8)

Guidance literature:

In ethanol; for 20h; Heating;

DOI:10.1055/s-1981-29611

Reference yield:

→ N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide (32255-42-8)

Guidance literature:

Homoveratrylamin, Isochromanon-(3);

Reference yield: 63.0%

N-<2-(3,4-dimethoxyphenyl)-ethyl>-2-(hydroxymethyl)-phenylacetamide (32255-42-8) + dimethyl sulfate (77-78-1) → 2-[2-(methoxymethyl)phenyl]-N-(3,4-dimethoxyphenethyl)acetamide

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/S0968-0896(01)00016-5

upstream raw materials:

isochroman-3-one

2-(3,4-dimethoxyphenyl)-ethylamine

Downstream raw materials:

2,3-dimethoxyberbine