Dapoxetine hydrochloride

Base Information

• Chemical Name: Dapoxetine hydrochloride
• CAS No.: 129938-20-1
• Molecular Formula: C21H24ClNO
• Molecular Weight: 341.8744
• Hs Code.: 29221990
• Mol file: 129938-20-1.mol

Synonyms:Benzenemethanamine,N,N-dimethyl-a-[2-(1-naphthalenyloxy)ethyl]-,hydrochloride, (S)-;LY 210448 hydrochloride;

Chemical Property of Dapoxetine hydrochloride

Chemical Property:

• Appearance/Colour: off-white cryst
• Vapor Pressure: 1.27E-09mmHg at 25°C
• Melting Point: 175-179 °C
• Boiling Point: 454.4 °C at 760 mmHg
• Flash Point: 132.6 °C
• PSA: 12.47000
• LogP: 5.71360
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO: ≥20mg/mL

Purity/Quality:

99% ^*data from raw suppliers

Dapoxetine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N
• Hazard Codes: Xn,N
• Statements: 22-36-50/53
• Safety Statements: 36-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Description: Dapoxetine hydrochloride, belonging to the class of SSRIs, was the first drug originally approved for the on-demand treatment of men with PE by seven European countries in 2008.Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2h.
• Uses: Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men.