Technology Process of O-{cyclohexyl-[4-(quinoxalin-2-ylmethoxy)-phenyl]-methyl}-hydroxylamine
There total 6 articles about O-{cyclohexyl-[4-(quinoxalin-2-ylmethoxy)-phenyl]-methyl}-hydroxylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / H2 / 10percent Pd/C / ethanol / 4 h / 20 °C
2: 2.9 g / K2CO3 / dimethylformamide / 48 h / 20 °C
3: Ph3P; diethyl azodicarboxylate / tetrahydrofuran / 14 h / 20 °C
4: hydrazine hydrate / ethanol; CH2Cl2 / 0.5 h / Heating
With
hydrogen; potassium carbonate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
10percent Pd/C;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;
1: Hydrogenolysis / 2: Alkylation / 3: Mitsunobu reaction / 4: Substitution;
DOI:10.1021/jm9904102
- Guidance literature:
-
With
hydrazine hydrate;
In
ethanol; dichloromethane;
for 0.5h;
Heating;
DOI:10.1021/jm9904102
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trichloroisocyanuric acid / CHCl3 / 0.5 h / Heating
2: 2.9 g / K2CO3 / dimethylformamide / 48 h / 20 °C
3: Ph3P; diethyl azodicarboxylate / tetrahydrofuran / 14 h / 20 °C
4: hydrazine hydrate / ethanol; CH2Cl2 / 0.5 h / Heating
With
trichloroisocyanuric acid; potassium carbonate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide;
1: Chlorination / 2: Alkylation / 3: Mitsunobu reaction / 4: Substitution;
DOI:10.1021/jm9904102
