(9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene

Base Information

• Chemical Name: (9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene
• CAS No.: 114790-83-9
• Molecular Formula: C₂₁H₂₈O₂S
• Molecular Weight: 344.518
• Mol file: 114790-83-9.mol

Synonyms:(9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene

Chemical Property of (9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene

There total 1 articles about (9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3S,6S,SS,1'R)-3,6-dimethyl-3-(3-hydroxy-1-methyl-2-methylenecyclopentyl)-1-(phenylsulfinyl)cyclohexene (114790-51-1,114882-96-1,114883-11-3,114883-12-4) → (9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene (114790-83-9) + (9S,10R,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene (114790-67-9)

Guidance literature:

With potassium hydroxide; In tert-butyl alcohol; at 83 ℃; for 3h;

DOI:10.1021/ja00222a036

Reference yield: 89.0%

(9S,10S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene (114790-83-9) → (+)-12,13-deoxytrichothec-9-ene (54713-64-3,60769-55-3,114883-14-6)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In various solvent(s); at 150 ℃; for 36h;

DOI:10.1021/ja00222a036

Reference yield: 70.0%

(9S,SS)-12,13-deoxy-9,10-dihydro-10-(phenylsulfinyl)trichothecene (114790-67-9,114790-83-9,114883-06-6,114883-07-7) → (+)-12,13-deoxytrichothec-9-ene (54713-64-3,60769-55-3,114883-14-6)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In various solvent(s); at 250 ℃; for 36h;

DOI:10.1021/ja00222a036

upstream raw materials:

(3S,6S,SS,1'R)-3,6-dimethyl-3-(3-hydroxy-1-methyl-2-methylenecyclopentyl)-1-(phenylsulfinyl)cyclohexene

Downstream raw materials:

(-)-12,13-epoxytrichothec-9-ene

(+)-12,13-deoxytrichothec-9-ene

(+)-12,13-epoxytrichothec-9-ene