1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile

Base Information

Chemical Name:1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile
CAS No.:85460-32-8
Molecular Formula:C₂₅H₁₅ClN₄S₂
Molecular Weight:471.006
Hs Code.:
Mol file:85460-32-8.mol

Synonyms:1-amino-2-(benzo[d]thiazol-2-yl)-3-(4-chlorophenyl)-3H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carbonitrile

Suppliers and Price of 1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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American Custom Chemicals Corporation
1-AMINO-2-(1,3-BENZOTHIAZOL-2-YL)-3-(4-CHLOROPHENYL)-3H-PYRIDO[2,1-B][1,3]BENZOTHIAZOLE-4-CARBONITRILE 95.00%
5MG
$ 497.54

Total 0 raw suppliers

Chemical Property of 1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile

Chemical Property:

Purity/Quality:: 1-AMINO-2-(1,3-BENZOTHIAZOL-2-YL)-3-(4-CHLOROPHENYL)-3H-PYRIDO[2,1-B][1,3]BENZOTHIAZOLE-4-CARBONITRILE 95.00% ^*data from reagent suppliers

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Technology Process of 1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile

There total 6 articles about 1-amino-2-(1,3-benzothiazol-2-yl)-3-(4-chlorophenyl)-3H-pyrido[2,1-b][1,3]benzothiazole-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 56278-50-3
2-cyanomethylbenzothiazole

: 85460-29-3
2-(benzo[d]thiazol-2-yl) ?3-(4-chlorophenyl)acrylonitrile

: 85460-32-8
1-amino-2-(benzo[d]thiazol-2-yl)-3-(4-chlorophenyl)-3H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carbonitrile

Guidance literature:: With piperidine; In ethanol; at 20 ℃; for 1.66667h; Sonication;
DOI:10.1016/j.molstruc.2021.130792

Reference yield: 37.0%

: 56278-50-3
2-cyanomethylbenzothiazole

: 104-88-1
4-chlorobenzaldehyde

: 85460-32-8
1-amino-2-(benzo[d]thiazol-2-yl)-3-(4-chlorophenyl)-3H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carbonitrile

Guidance literature:: With triethylamine; In tetrahydrofuran; for 8h; Heating;
DOI:10.1055/s-1983-30284

Reference yield:

: 137-07-5
2-amino-benzenethiol

: 85460-32-8
1-amino-2-(benzo[d]thiazol-2-yl)-3-(4-chlorophenyl)-3H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / acetic acid / ethanol / 3 h / Heating

2: 64 percent / triethylamine / tetrahydrofuran / 6 h / Heating

With acetic acid; triethylamine; In tetrahydrofuran; ethanol;
DOI:10.1055/s-1983-30284