2-Bromo-2,2-diphenylacetyl chloride

Base Information

• Chemical Name: 2-Bromo-2,2-diphenylacetyl chloride
• CAS No.: 17397-37-4
• Molecular Formula: C14H10 Br2 O
• Molecular Weight: 354.041
• Hs Code.: 2916399090
• European Community (EC) Number: 241-423-2
• DSSTox Substance ID: DTXSID90169736
• Nikkaji Number: J236.207D
• Wikidata: Q83039484
• Mol file: 17397-37-4.mol

Synonyms:2-Bromo-2,2-diphenylacetyl bromide;2-Bromo-2,2-diphenylacetyl chloride;17397-37-4;EINECS 241-423-2;C14H10Br2O;SCHEMBL8059880;Bromo(diphenyl)acetyl bromide #;C14-H10-Br2-O;DTXSID90169736;2-Bromo-2,2-diphenylacetic acid bromide;Benzeneacetyl bromide, .alpha.-bromo-.alpha.-phenyl-

Chemical Property of 2-Bromo-2,2-diphenylacetyl chloride

Chemical Property:

• Vapor Pressure: 2.19E-05mmHg at 25°C
• Boiling Point: 360.6°C at 760 mmHg
• Flash Point: 88.1°C
• PSA: 17.07000
• Density: 1.688g/cm³
• LogP: 4.24660
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 353.90779
• Heavy Atom Count: 17
• Complexity: 247

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)Br)Br

Technology Process of 2-Bromo-2,2-diphenylacetyl chloride

There total 4 articles about 2-Bromo-2,2-diphenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenyl ketene (525-06-4) → α,α-bromodiphenylacetyl bromide (17397-37-4)

Guidance literature:

With bromine; In dichloromethane; at 30 ℃; Rate constant; Mechanism;

DOI:10.1021/jo00346a007

Reference yield:

Benzilic acid (76-93-7) → α,α-bromodiphenylacetyl bromide (17397-37-4)

Guidance literature:

With phosphorus pentabromide;

Reference yield:

9-hydroxy-9-fluorene carboxylic acid (467-69-6) + phosphorus pentabromide (7789-69-7) → α,α-bromodiphenylacetyl bromide (17397-37-4)

Guidance literature:

upstream raw materials:

diphenyl ketene

Benzilic acid

9-hydroxy-9-fluorene carboxylic acid

phosphorus pentabromide

Downstream raw materials:

bromo-diphenyl-acetic acid anilide

benzilic acid tropane-3exo-yl ester

1-Brom-4-(N-methylanilino)-1,1-diphenyl-3-butin-2-on

diphenyl ketene

Refernces

• 1、 Ogata, Yoshiro,Adachi, Koichi. "Monoacyl Sulfates as Intermediates for α-Halogenation of Aliphatic Acids". . p. 1182 - 1184. Retrieved 2007/10/02.