S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

Base Information

Chemical Name:S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite
CAS No.:1192047-83-8
Molecular Formula:C₃₈H₅₅N₂O₃PS
Molecular Weight:650.906
Hs Code.:

Synonyms:S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

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Technology Process of S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

There total 1 articles about S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1036914-96-1
2,2-dimethyl-3-(trityloxy)propanoic acid

: 56183-63-2
bis(diisopropylamino)chlorophosphine

: 1192047-83-8
S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

Guidance literature:: With triethylamine; In diethyl ether; at -15 - 20 ℃; for 5h; Inert atmosphere;

Reference yield:

: 1192047-83-8
S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl-di(N,N-diisopropylamino)phosphorobisamidite

: 108-95-2,27073-41-2
phenol

: 1192047-87-2
O-phenyl S-(2,2-dimethyl-3-triphenylmethoxypropionyl)-2-thioethyl N,N-diisopropyl-aminophosphoramidite

Guidance literature:: With 1H-tetrazole; diisopropylamine; In acetonitrile; at 0 - 20 ℃; for 2.25h; Molecular sieve;
DOI:10.1016/j.bmc.2009.07.038