[2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester

Base Information

• Chemical Name: [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester
• CAS No.: 955403-38-0
• Molecular Formula: C₁₆H₂₁N₃O₂
• Molecular Weight: 287.362
• Mol file: 955403-38-0.mol

Synonyms:[2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester

Chemical Property of [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester

There total 2 articles about [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethylamine (955403-37-9) + benzyl chloroformate (501-53-1,94274-21-2) → [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester (955403-38-0)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; water; at 0 ℃; for 0.5h;

Reference yield: 29.0%

(2-ethyl-5-methyl-2H-pyrazol-3-yl)-acetonitrile (955403-36-8) + benzyl chloroformate (501-53-1,94274-21-2) → [2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester (955403-38-0)

Guidance literature:

(2-ethyl-5-methyl-2H-pyrazol-3-yl)-acetonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;

benzyl chloroformate; With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1016/j.bmcl.2010.01.070

Reference yield: 94.0%

[2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethyl]-carbamic acid benzyl ester (955403-38-0) → 2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethylamine (955403-37-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃;

DOI:10.1016/j.bmcl.2010.01.070

upstream raw materials:

(2-ethyl-5-methyl-2H-pyrazol-3-yl)-acetonitrile

benzyl chloroformate

2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethylamine

Downstream raw materials:

2-(2-ethyl-5-methyl-2H-pyrazol-3-yl)-ethylamine

1-ethyl-3-methyl-4-[2-(4-trifluoromethyl-phenyl)-ethyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine