(N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester

Base Information

• Chemical Name: (N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester
• CAS No.: 160811-80-3
• Molecular Formula: C₂₉H₃₁N₃O₃
• Molecular Weight: 469.583
• Mol file: 160811-80-3.mol

Synonyms:(N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester

Chemical Property of (N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester

There total 2 articles about (N^2',N^2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(S)-2-Dimethylamino-1-imidazol-1-yl-3-phenyl-propan-1-one + L-tryptophan benzyl ester hydrochloride (22839-16-3) → (N2',N2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester (160811-80-3)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1002/hlca.19940770726

Reference yield:

(2S)-2-(dimethylamino)-3-phenylpropanoic acid (17469-89-5) → (N2',N2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester (160811-80-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 0.75 h / Ambient temperature

2: 85 percent / 1H-imidazole / dimethylformamide / Ambient temperature

With 1H-imidazole; In N,N-dimethyl-formamide;

DOI:10.1002/hlca.19940770726

Reference yield: 90.0%

(N2',N2'-dimethyl-L-phenylalanyl)-L-tryptophan benzyl ester (160811-80-3) → (N2',N2'-dimethyl-L-phenylalanyl)-L-tryptophan

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 0.5h; Ambient temperature;

DOI:10.1002/hlca.19940770726

upstream raw materials:

L-tryptophan benzyl ester hydrochloride

(2S)-2-(dimethylamino)-3-phenylpropanoic acid